bs-82608C
[Life Science]
Z-DEVD-FMK
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Lyophilized solid
Storage: -20°C
Product Information:
Z-DEVD-FMK (210344-95-9) is a cell-permeable trimethyl ester form of the irreversible caspase-3 inhibitor DEVD-FMK (fluoromethylketone) with IC50 = 130 nM.1,2 Methyl esters confer cell permeability and are hydrolyzed to the active COOH form via intracellular esterases. Inhibits caspase-3-dependent apoptosis and pyroptosis in a variety of cell lines.3,4 Active in vivo.5
Description:
CAS Number: 210344-95-9; Chemical Name: Benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone; Molecular weight: 668.67; Formula: C30H41FN4O12; Solubility: DMSO (20 mg/ml); Physical Properties: Lyophilized solid; Purity: >98% by TLC, NMR (Conforms)
Size: 1mg
Applications: Life Science(N/A)
For research use only. Not intended for diagnostic or therapeutic use.