DATASHEET
Formulation
Off-White solid
Storage:
RT
Product Information:
Potent inhibitor of prolyl 4-hydroxylase (IC50=2-4 μM)1. Inhibits collagen deposition via inhibition of collagen proline hydroxylation2,3. Subcutaneous injection of a 1,4-DPCA containing hydrogel into Swiss Webster mice that do not show a regenerative phenotype increased expression of HIF1α over 5 days. Multiple injections led to regenerative wound healing after ear hole punch injury4.
Description:
CAS Number: 331830-20-7; Chemical Name: 1,4-Dihydrophenonthrolin-4-one-3-carboxylic acid; Molecular weight: 240.22; Formula: C13H8N2O3; Solubility: DMSO 15 mg/ml; Physical Properties: Off-white solid; Purity: 98% by HPLC, NMR (Conforms)