DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Cinacalcet (364782-34-3) is a calcimimetic that allosterically activates the calcium-sensing receptor (CaSR; EC50 = 79.4 nM in HEK 293T cells expressing CaSR).1-3 It lowers plasma parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism.4 Cinacalcet has been used to treat parathyroid carcinoma.5
Description:
CAS Number: 364782-34-3<br></br>Chemical Name: αR-Methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine hydrochloride<br></br>Molecular weight: 393.88<br></br>Formula: C22H22F3N • HCl<br></br>Solubility: DMSO (50 mg/ml) Water (5 mg/ml with warming)<br></br>Physical Properties: White solid<br></br>Purity: >98% by TLC NMR (Conforms)