bs-82647C
[Life Science]
ABT-263
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Potent and selective Bcl-2 family inhibitor / BH3 domain mimetic which binds to Bcl-2, Bcl-xL and Bcl-w (Ki<1 nM). A useful tool compound which has shown interesting results in various cancer clinical trials2. Synergizes with deoxyglucose and other agents, inducing apoptosis in cancer cells in a xenograft mouse model3. A novel senolytic agent, inducing apoptosis preferentially in senescent cells in a cell type-restricted manner4.
Description:
CAS Number: 923564-51-6<br></br>Chemical Name: 4-[4-[[2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)- 3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]-phenyl]sulfonyl]-benzamide<br></br>Molecular weight: 974.6<br></br>Formula: C47H55ClF3N5O6S3<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC (NMR Conforms)
Size: 5mg, 25mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.