bs-82664C

DATASHEET

Formulation White Solid

Storage: -20°C

Product Information:

A potent inhibitor of VEGFR2 and R3, IC50s=4.0 and 5.2 nM respectively.1 Also inhibits VEGFR1, FGFR1, PDGFR3b and Kit, IC50s=22, 46, 39 and 100 nM respectively.1 Suppresses lymph node and lung metastasis in human mammary breast tumor model.2 Suppresses tumor cell migration and invasion.3 Inhibits angiogenesis.4

Description:

CAS Number: 417716-92-8; Chemical Name: 4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide; Molecular weight: 426.85; Formula: C21H19ClN4O4; Solubility: DMSO (20 mg/ml); Physical Properties: White solid; Purity: 98% by HPLC, NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.