DATASHEET
Formulation
White Solid
Storage:
-20°C
Product Information:
Ferroptosis inducer.1 Inhibits the cystine-glutamate antiporter, system Xc- leading to activation of an ER stress response.2 Inhibition of system Xc- leads to cysteine starvation, glutathione depletion and induction of ferroptosis.3 Also blocks mitochondrial voltage-dependent anion channels (specifically VDAC2 and 3).4
Description:
CAS Number: 571203-78-6; Chemical Name: 2-[1-[4-[2-(4-Chlorophenyoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone; Molecular weight: 547.04; Formula: C30H31ClN4O4; Solubility: DMSO (10 mg/ml); Physical Properties: White solid; Purity: 98% by HPLC, NMR (Conforms)