bs-82693C
[Life Science]
R-59022
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800.501.7654 [DOMESTIC]
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White Solid
Storage: -20°C
Product Information:
R-59022 is a diacylglycerol kinase (DAGK) inhibitor, nonselective for DAGK isotypes (IC50=2.8 µM in intact platelets).1 Induces autophagy and apoptosis in NG108-15 neuronal cells via an mTOR-independent mechanism.2 Prevents conjugated linoleic acid-mediated inflammatory signaling and insulin resistance in human adipocytes.3 Blocks filovirus internalization in host cells.4
Description:
CAS Number: 93076-89-2; Chemical Name: 6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one; Molecular weight: 459.58; Formula: C27H26FN3OS; Solubility: DMSO (25 mg/ml); Physical Properties: White solid; Purity: 98% by HPLC, NMR (Conforms)
Size: 5mg, 25mg
Applications: Life Science(N/A)
For research use only. Not intended for diagnostic or therapeutic use.