bs-82709C
[Life Science]
Eltrombopag
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Orange solid
Storage: -20°C
Product Information:
A novel, orally active, small molecule human thrombopoietin receptor (TPO-R) agonist, EC50=0.27 M.1,2 Maintains human hematopoietic stem and progenitor cells under inflammatory conditions.3 Promotes DNA repair in human hematopoietic stem and progenitor cells.4 Acts as a powerful chelator of cellular and extracellular iron(III).5 Stimulates hematopoietic stem cells via a TPO-R-independent mechanism involving iron chelation.6
Description:
CAS Number: 496775-61-2; Chemical Name: 3’-[2-[(2Z)-1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2’-hydroxy-[1,1’-biphenyl]-3-carboxylic acid; Molecular weight: 442.47; Formula: C25H22N4O4; Solubility: DMSO (55 mg/ml) Ethanol (14 mg/ml); Physical Properties: Orange solid; Purity: 98% by TLC NMR (Conforms)
Size: 5mg, 25mg
Applications: Life Science(N/A)
For research use only. Not intended for diagnostic or therapeutic use.