bs-82736C

DATASHEET

Formulation White to off-white solid

Storage: -20°C

Product Information:

EN450 is a molecular glue that covalently interacts with a cysteine residue on the E2 ubiquitin ligase UBE2D. It displayed anti-proliferative effects in HAP1 leukemia cells. EN450s antiproliferative effects were elicited via proteasome-dependent degradation of nuclear factor kappa B subunit 1(NFkB1).1

Description:

CAS Number: 793719-01-4; Chemical Name: N-(2-Chloro-5-(N,N-dimethylsulfamoyl)phenyl)acrylamide; Molecular weight: 288.75; Formula: C11H13ClN2O3S; Solubility: DMSO (>80 mg/ml); Physical Properties: White to off-white solid; Purity: >98% by HPLC , NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.