DATASHEET
Formulation
White Solid
Storage:
-20°C
Product Information:
Pan-agonist of the estrogen receptor-related receptors (EC50’s cell-based cotransfection/reporter assay: ERRα = 98 nM, ERRß = 230 nM, ERRγ = 430 nM) with highest potency for ERRα.1,2 SLU-PP-332 increased mitochondrial function and cellular respiration in a skeletal muscle cell line.2 It also increased fast oxidative skeletal muscle fibers (Type IIa) and exercise endurance in mice in an ERRα-specific manner. SLU-PP-332 activates an acute aerobic exercise genetic response via inducing the expression of DDIT4.2
Description:
CAS Number: 303760-60-3; Chemical Name: (E)-4-Hydroxy-N’-(naphthalen-2-ylmethylene)benzohydrazide; Molecular weight: 290.32; Formula: C18H14N2O2; Solubility: DMSO (75 mg/ml); Physical Properties: White solid; Purity: >98% by HPLC , NMR (Conforms)