bs-82774C

DATASHEET

Formulation Off-White solid

Storage: -20°C

Product Information:

Potent (IC50 = 11 nM) inhibitor of flap endonuclease 1 (FEN1).1 It showed similar potency in inhibiting exonuclease 1 (EXO1).2 Induces a DNA damage response and ultimately cell death. FEN1 inhibitors have therapeutic potential for the treatment of cancers that are defective for homologous repair and other DNA repair and DNA damage checkpoint pathways.4

Description:

CAS Number: 824983-91-7; Chemical Name: 1-(2,3-Dihydro-1,4-benzodioxin-3-ylmethyl)-3-hydroxythieno[3,2-d]pyrimidine-2,4-dione; Molecular weight: 332.33; Formula: C15H12N2O5S; Solubility: DMSO (15 mg/ml); Physical Properties: Off-white solid; Purity: 98% by TLC , NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.