bs-82777C

DATASHEET

Formulation White Solid

Storage: -20°C

Product Information:

BET inhibitor 220-fold more selective for BD2 over BD1 (pIC50 BD2 = 7.1; BD1 = 4.8).1 It ameliorated collagen-induced arthritis in a rat model and imiquimod-induced psoriasis in a mouse model.2 GSK620 was also able to reduce hepatic fibrosis, steatosis, and inflammation in a mouse model of non-alcoholic steatohepatitis (NASH).

Description:

CAS Number: 2088410-46-0; Chemical Name: 1-Benzyl-5-N-cyclopropyl-3-N-methyl-2-oxopyridine-3,5-dicarboxamide; Molecular weight: 325.37; Formula: C18H19N3O3; Solubility: DMSO (25 mg/ml); Physical Properties: White solid; Purity: >98% by HPLC NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.