bs-82778C
[Life Science]
CPI203
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White to off-white solid
Storage: -20°C
Product Information:
CPI203, a JQ1 analog, is a potent and selective inhibitor of the BET bromodomain BRD4 (IC50 = 26 nM).1 It helps promote the maintenance of hematopoietic stem cells via repression of Myc expression.2 CPI203 reversibly suppressed intestinal stem cell differentiation in a mouse model.3 It enhanced the expansion of human cord blood hematopoietic stem cells without losing cell viability.4 CPI203 displays synergistic antitumor activity with various agents including lenalidomide5, bortezomib6, and PARP inhibitors7.
Description:
CAS Number: 1446144-04-2<br></br>Chemical Name: (S)-2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6h-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamide<br></br>Molecular weight: 399.9<br></br>Formula: C19H18ClN5OS<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: White to off-white solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 5mg, 25mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.