bs-82780C

DATASHEET

Formulation Pale yellow solid

Storage: -20°C

Product Information:

Raltitrexed is an inhibitor of thymidylate synthase with significantly increased potency in many cancer cell lines when compared with 5-fluorouracil.1,2 It is also an inhibitor of the methyltransferase G9a (IC50 = 120 nM) and decreased Aß aggregates in C. elegans indicating therapeutic potential for the treatment of Alzheimer’s disease.3

Description:

CAS Number: 112887-68-0; Chemical Name: (2S)-2-[[5-[Methyl-[(2-methyl-4-oxo-3H-quinazolin-6-yl)methyl]amino]thiophene-2-carbonyl]amino]pentanedioic acid; Molecular weight: 458.49; Formula: C21H22N4O6S; Solubility: DMSO (>25 mg/ml); Physical Properties: Pale yellow solid; Purity: >98% by HPLC NMR (Conforms)

Size: 10mg, 50mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.