bs-82799C

DATASHEET

Formulation Pale yellow solid

Storage: -20°C

Product Information:

Potent (IC50 = 104 nM) and selective inhibitor of protein lysine methyltransferase nuclear receptor-binding SET domain-containing 2 (NSD2). It potently binds to the PWWP1 domain antagonizing interaction with nucleosomal H3K36me2. UNC6934 is selective against 14 other human PWWP domains and 33 methyltransferases. Active in a nanoBRET PPI assay in U2OS cells (IC50 = 1.23 µM).

Description:

CAS Number: 2561494-77-5; Chemical Name: N-Cyclopropyl-3-oxo-N-(4-pyrimidin-4-ylcarbamoyl)benzyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carboxamide; Molecular weight: 443.46; Formula: C24H21N5O4; Solubility: DMSO (>25 mg/ml); Physical Properties: Pale yellow solid; Purity: 98% by HPLC NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.