bs-82820C
[Life Science]
NE-100
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800.501.7654 [DOMESTIC]
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White Solid
Storage: -20°C
Product Information:
NE-100 is potent inhibitor of the sigma receptor () with selectivity for sigma-1 (IC50 = 1.5 nM) over sigma-2 (IC50 = 85 nM).1,2 NE-100 suppressed ischemia-induced neuronal cell death in mice via upregulation of GPR78 through the ATF6 pathway resulting in suppression of ER stress-induced cell death in a sigma 1 independent manner.3
Description:
CAS Number: 149409-57-4; Chemical Name: 4-Methoxy-3-(2-phenylethoxy)-N,N,dipropylbenzeneethanamine hydrochloride; Molecular weight: 391.97; Formula: C23H33NO2·HCl; Solubility: DMSO (>25 mg/ml) Water (10 mg/ml); Physical Properties: White solid; Purity: 98% by HPLC NMR (Conforms)
Size: 5mg, 25mg
Applications: Life Science(N/A)
For research use only. Not intended for diagnostic or therapeutic use.