bs-82856C

DATASHEET

Formulation White Solid

Storage: RT

Product Information:

Bedaquiline is a clinically useful antituberculosis agent that is active (MIC’s 0.030 to 0.120 µg/mL) against multi-drug resistant strains.1 It interferes with mycobacterial energy metabolism via binding to the oligomeric subunit c (AtpE)2 and subunit 3 of ATP synthase inhibiting ATP production.4 Bedaquiline has recently been found to be an inhibitor (IC50 = 18.7 µM) of the SARS-CoV-2 main protease, 3CLpro.5

Description:

CAS Number: 843663-66-1; Chemical Name: (1R,2S)-1-(6-Bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol; Molecular weight: 555.50; Formula: C32H31BrN2O2; Solubility: DMSO (10 mg/ml); Physical Properties: White solid; Purity: 99% by HPLC, NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.