DATASHEET
Formulation
White to off-white glassy solid
Storage:
-20°C
Product Information:
TH257 is a potent (IC50’s = 238 nM (LIMK1) and 91 nM (LIMK2)) and highly selective (no off-targets against 468 kinases) allosteric inhibitor of LIM kinase 1/2.1 It inhibited neurite outgrowth in N1E-115 cells in a dose-dependent manner.
Description:
CAS Number: 2244678-29-1; Chemical Name: N-Butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)benzamide; Molecular weight: 422.54; Formula: C24H26N2O3S; Solubility: DMSO (25 mg/ml); Physical Properties: White to off-white glassy solid; Purity: >98% by HPLC NMR (Conforms)