DATASHEET
Formulation
Off-White solid
Storage:
-20°C
Product Information:
LDC1267 is a potent and selective inhibitor of the TAM kinases Tyro3, Axl, and Mer (IC50s respectively: 8 nM, <5 nM, 29 nM).1 It was able to activate the innate immune system and enhance NK killer cell activity to kill cancer metastases in vivo.
Description:
CAS Number: 1361030-48-9; Chemical Name: N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluoro-2-methylphenyl)-1H-pyrazole-3-carboxamide; Molecular weight: 560.56; Formula: C30H26F2N4O5; Solubility: DMSO (25 mg/ml); Physical Properties: Off-white solid; Purity: >98% by HPLC NMR (Conforms)