bs-82863C
[Life Science]
Epalrestat
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Yellow solid
Storage: -20°C
Product Information:
Epalrestat is an aldose reductase inhibitor (IC50 = 10 nM (rat lens) and 25 nM (human placenta).1,2 It reduces sorbitol accumulation in the sciatic nerve, erythrocytes and ocular tissue. May be used to prevent or slow the progression of diabetic neuropathy.3
Description:
CAS Number: 82159-09-9<br></br>Chemical Name: 2-[(5Z)-5-[(E)-3-phenyl-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic acid<br></br>Molecular weight: 319.40<br></br>Formula: C15H13NO3S2<br></br>Solubility: DMSO (5 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: >98% (TLC: 5% Methanol/methylene chloride + 0.5% HOAc; Rf = 0.21)
Size: 5mg, 25mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.