DATASHEET
Formulation
beige solid
Storage:
-20°C
Product Information:
Potent (AC50 = 29 nM PKR; 37 nM PKM2; 33 nM PKL) allosteric activator of pyruvate kinase.1 In clinical use for the treatment of hemolytic anemia2 and a potential agent for the treatment for ß-thalassemia3 and sickle cell anemia4.
Description:
CAS Number: 1260075-17-9; Chemical Name: N-[4-[4-(Cyclopropylmethyl)piperazine-1-carbonyl]phenyl]quinoline-8-sulfonamide; Molecular weight: 450.56; Formula: C24H26N4O3S; Solubility: DMSO (>50 mg/ml); Physical Properties: Beige solid; Purity: 99% by HPLC NMR (Conforms)