bs-82885C
[Life Science]
Afatinib
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Pale yellow solid
Storage: -20°C
Product Information:
Afatinib is a clinically useful kinase inhibitor approved for the treatment of non-small cell lung cancer. It is a potent and highly selective inhibitor of mutant and wild-type EGFR (IC50 = 0.5 nM) and HER2 (IC50 = 14 nM).
Description:
CAS Number: 850140-72-6<br></br>Chemical Name: N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4(dimethylamino)-2E-butenamide<br></br>Molecular weight: 485.94<br></br>Formula: C24H25ClFN5O3<br></br>Solubility: DMSO (>25 mg/ml) Ethanol (25 mg/ml)<br></br>Physical Properties: Pale yellow solid<br></br>Purity: 99% by HPLC, NMR (Conforms)
Size: 10mg, 50mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.