bs-82889C
[Life Science]
GW1100
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800.501.7654 [DOMESTIC]
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Selective antagonist of GPR40. GW1100 inhibits GRP40-mediated Ca2+ increases stimulated GW9508 or linoleic acid (pIC50 = 5.99 for either agonist).1 The effects of GPR40 activation on insulin secretion in cells are also blocked by the addition of GW1100.
GW1100 does not influence calcium mobilization mediated by GPR120.
Description:
CAS Number: 305974-70-9<br></br>Chemical Name: 1-(4-Ethoxycarbonylphenyl-2-(4-fluorobenzylthio)-5-(2-ethoxy-5-pyrimidinylmethyl)-4-pyrimidinone<br></br>Molecular weight: 520.59<br></br>Formula: C27H25FN4O4S<br></br>Solubility: DMF (5 mg/ml) DMSO (2 mg/ml<br></br>Physical Properties: White solid<br></br>Purity: 96% by LCMS NMR (Conforms)
Size: 5mg, 25mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.