bs-82912C
[Life Science]
RepSox
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Pale yellow solid
Storage: -20°C
Product Information:
RepSox is a potent (IC50 ALK5 auto-P= 4 nM; IC50 TGF-b cellular assay = 23 nM) inhibitor of the TGF-β type I receptor (ALK5).1 RepSox can replace Sox2 in reprogramming adult cells into pluripotent stem cells via induction of Nanog transcription.2 It was able to convert astrocytes into neuronal cells as part of a small molecule cocktail (along with valproic acid and CHIR99021).3,4
Description:
CAS Number: 446859-33-2<br></br>Chemical Name: 2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine; E-616452; SNJ 2511<br></br>Molecular weight: 287.32<br></br>Formula: C17H13N5<br></br>Solubility: DMSO (>25 mg/ml) Ethanol (10 mg/ml)<br></br>Physical Properties: Pale yellow solid<br></br>Purity: 99% by HPLC, NMR (Conforms)
Size: 5mg, 25mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.