bs-82916C

DATASHEET

Formulation White Solid

Storage: -20°C

Product Information:

Mitoguazone is a potent and reversible inhibitor of S-adenosylmethionine decarboxylase (SAMD or AdoMetDC).1,2 SAMD is a component of the polyamine-biosynthetic pathway, thus inhibition may lead to changes in polyamine metabolism.3 Mitoguazone has also been shown to inhibit diamine oxidase and induce spermidine/spermine N-acetyltransferase.4,5 Mitoguazone has been looked at as a potential anti-cancer treatment because of it’s ability to inhibit polyamine synthesis.6

Description:

CAS Number: 31959-87-2; Chemical Name: Methylglyoxal bis(guanylhydrazone) dihydrochloride; Molecular weight: 257.13; Formula: C5H12N8 · 2HCl; Solubility: water (>25 mg/ml) DMSO (?); Physical Properties: White solid; Purity: 98% by HPLC, NMR (Confirms)

Size: 10mg, 50mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.