DATASHEET
Formulation
White Solid
Storage:
-20°C
Product Information:
BML283 is a selective activator of the Tumor Specific M2 Isoform of Pyruvate Kinase (PKM2) - AC50 = 111nM.1 PKM2 activity is downregulated in most cancer cells leading to a decrease in catabolic metabolism and an increase in anabolic metabolism.2,3 BML283 is an important tool for studying the effects of PKM2 and cancer metabolism.
Description:
CAS Number: 562867-96-3; Chemical Name: 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)-4-(4-methoxyphenylsulfonyl)piperazine; Molecular weight: 454.51; Formula: C19H22N2O7S2; Solubility: DMSO (10 mg/ml); Physical Properties: white solid; Purity: 98% by TLC, NMR (Conforms)