DATASHEET
Formulation
Off-White solid
Storage:
-20°C
Product Information:
L-γ-Glutamyl-p-nitroanilide (GPNA) is a substrate for γ-glutamyl transpeptidase. GPNA is used for the determination of γ-glutamyl transpeptidase hydrolytic activity via spectrophotometric monitoring of p-nitroaniline released by the action of the enzyme on GPNA.1 GPNA has also been shown to be an inhibitor of glutamine uptake – solute-linked carrier family A1 member 5 (SLC1A5)2 Cellular uptake of L-glutamine (regulated by SLC1A5) is a rate-limiting step that activates mTOR and is, thus, an interesting cancer chemotherapy target.3
Description:
CAS Number: 67953-08-6; Chemical Name:; Molecular weight: 303.70; Formula: C11H13N3O5 · HCl; Solubility: Water (5 mg/ml); Physical Properties: Off-white solid; Purity: 98%