bs-82960C
[Life Science]
PF-9366
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Beige solid
Storage: -20°C
Product Information:
PF-9366 is an allosteric inhibitor (IC50 = 420 nM) of methionine adenosyltransferase 2A (Mat2A), the primary enzyme responsible for extrahepatic synthesis of S-adenosyl-L-methionine (SAM).1 It inhibited cellular SAM production in H520 lung and Huh-7 liver cancer cells with IC50’s of 1.2 µM and 225 nM respectively.
Description:
CAS Number: 72882-78-1<br></br>Chemical Name: 2-(7-Chloro-5-phenyl)-[1,2,4]triazolo[4,3-a]quinoline-1-yl)-N,N,dimethylethanamine<br></br>Molecular weight: 350.85<br></br>Formula: C20H19ClN4 <br></br>Solubility: DMSO (20 mg/ml)<br></br>Physical Properties: Beige solid<br></br>Purity: 98% by TLC NMr (Conforms)
Size: 25mg, 5mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.