DATASHEET
Formulation
White Solid
Storage:
-20°C
Product Information:
Histamine H1 antagonist with anti-muscarinic effects at the M1 receptor. Enhances remyelination in a mouse model of demyelination.1 Displays protective role against neuroinflammation and demyelination via anti-inflammatory and anti-pyroptotic actions.2 Clemastine promoted oligodendrocyte differentiation in a rat model of spinal cord injury via muscarinic receptor mediated activation of ERK1/2 signaling.3
Description:
CAS Number: 14976-57-9; Chemical Name: (2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine fumarate; Molecular weight: 459.96; Formula: C21H26ClNO·C4H4O4; Solubility: DMSO (25 mg/ml); Physical Properties: White solid; Purity: >98% by TLC NMR (Conforms)