bs-82967C
[Life Science]
VU0134992
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Off-white/tan solid
Storage: -20°C
Product Information:
VU0134992 is a blocker of the inward rectifier potassium channel Kir4.1 (IC50 = 970 nM).1 It also inhibits Kir3.1/3.2, Kir3.1/3.4, and Kir4.2 with similar potency. VU0134992 induced diuresis, natriuresis, and kaliuresis in Sprague-Dawley rats suggesting therapeutic blood pressure lowering potential. It reduced polymyxin-induced nephrotoxicity in cell culture and mouse explant kidney tissue.2
Description:
CAS Number: 755002-90-5<br></br>Chemical Name: 2-(2-Bromo-4-propan-2-yl)phenoxy)-N-(2,2,6,6-tetramethlpiperidin-4-yl)acetamide<br></br>Molecular weight: 411.38<br></br>Formula: C20H31BrN2O2<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: Off-white/tan solid<br></br>Purity: 98% by TLC NMR (Conforms)
Size: 25mg, 5mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.