bs-82986C [Life Science]
CBR-470-1
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Formulation White Solid

Storage: -20°C

Product Information:

Activator of NRF2 signaling (EC50 ~ 1 µM cellular ARE-LUC assay).1 It inhibits phosphoglycerate kinase 1 leading to a build-up of methylglyoxal which inactivates KEAP1. It protected SH-SY5Y neuronal cells from MPP+ induced oxidative injury via activation of NRF2 signaling.2

Description:

CAS Number: 2416095-06-0; Chemical Name: trans-4-(4-Chlorophenyl)sulfonyl-N-(2-methylpropyl)-1,1-dioxothiolan-3-amine; Molecular weight: 365.89; Formula: C14H20ClNO4S2; Solubility: DMSO (>25 mg/ml); Physical Properties: White solid; Purity: 98% by HPLC NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.