bs-82990C [Life Science]
Glumetinib
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Formulation Beige solid

Storage: -20°C

Product Information:

Highly selective (2400-fold selectivity against a panel of 312 kinases) and potent (IC50 = 0.42 nM) inhibitor of c-Met kinase. It induced tumor regression in MET-driven CDX (MKN-45, SNU-5, EBC-1) and PDX (4 NSCLC, 5 HCC) tumor models.

Description:

CAS Number: 1642581-63-2<br></br>Chemical Name: 6-(1-Methylpyrazol-4-yl)-1-[6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-yl]sulfonylpyrazolo[4,3-b]pyridine<br></br>Molecular weight: 459.48<br></br>Formula: C21H17N9O2S<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: Beige solid<br></br>Purity: 98% by HPLC NMR (Conforms)

Size: 25mg, 5mg

Applications: Life Science

For research use only. Not intended for diagnostic or therapeutic use.