bs-82999C

DATASHEET

Formulation Off-White solid

Storage: -20°C

Product Information:

KC7F2 is an inhibitor of HIF-1α (IC50 = 20 µM).1 It inhibited HIF-mediated transcription in cells derived from glioma, breast, and prostate cancers. The mechanism of action of KC7F2 is via down-regulation of HIF-1α protein synthesis accompanied by suppression of phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 and p70 S6 kinase, key regulators of HIF-1α protein synthesis.

Description:

CAS Number: 927822-86-4; Chemical Name: N,N'-(Dithiodi-2,1-ethanediyl)bis[2,5-dichlorobenzenesulfonamide; Molecular weight: 570.38; Formula: C16H16Cl4N2O4S4; Solubility: DMSO (>25 mg/ml); Physical Properties: Off-white solid; Purity: 98% by HPLC, NMR (Conforms)

Size: 10mg, 50mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.