bs-83020C

DATASHEET

Formulation White Solid

Storage: -20°C

Product Information:

Binimetinib (606143-89-9) is a potent (IC50 = 12 nM) and selective allosteric inhibitor of MEK1/2.1,2 Recently approved by the FDA for treatment of melanoma in combination with Encorafenib. Binimetinib has had limited success as monotherapy but has shown promise in combination with other chemotherapeutic agents.3-5

Description:

CAS Number: 606143-89-9; Chemical Name: 6-(4-Bromo-2-fluoroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide; Molecular weight: 441.23; Formula: C17H15BrF2N4O3; Solubility: DMSO (25 mg/ml); Physical Properties: White solid; Purity: 99% by HPLC NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.