bs-83029C [Life Science]
NU7441
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Formulation Off-white to beige solid

Storage: -20°C

Product Information:

NU7441 is a potent (IC50 = 13 nM) and selective ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK).1,2 It increased the toxicity of ionizing radiation and etoposide on SW620 human colon cancer lines via impeding of DNA double-strand break repair.3 NU7441 also increased the radio/chemosensitivity of various other cancer cell lines.3-6

Description:

CAS Number: 503468-95-9; Chemical Name: 8-Dibenzothiophen-4-yl-2-morpholin-4-ylchromen-4-one; Molecular weight: 413.49; Formula: C25H19NO3S; Solubility: DMSO (10 mg/ml); Physical Properties: Off-white to beige solid; Purity: 98% by TLC NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.