DATASHEET
Formulation
yellow solid
Storage:
-20°C
Product Information:
Linsitinib is a potent and selective dual inhibitor of insulin-like growth factor 1 (IGF-1R) kinase and insulin receptor (InsR) kinase (IC50’s = 35 and 75 nM respectively).1 It has been investigated as a chemotherapeutic in combination with other drugs for various cancers.2-6
Description:
CAS Number: 867160-71-2; Chemical Name: 3-[8-Amino-1-(2-phenyl-7-quinolyl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutanol; Molecular weight: 421.49; Formula: C26H23N5O; Solubility: DMSO (30 mg/ml); Physical Properties: Yellow solid; Purity: 98% by HPLC NMR (Conforms)