DATASHEET
Formulation
Pale-yellow solid
Storage:
-20°C
Product Information:
A naturally occurring alkaloid from Stephania cepharantha Hayata which possesses a number of pharmacological activities.1 Attenuates LPS-induced expression of TNF-, IL-6 and IL-1 in macrophages and inhibits NF-B activation.2 Induces mitophagy possibly by acting at GPR30 in hepatocellular carcinoma.3 Inhibits autophagosome-lysosome fusion and autophagy by downregulation of MYO1C an actin-based motor protein.4 Potently inhibits replication of SARS CoV-2 and homologous viruses.5
Description:
CAS Number: 481-49-2; Chemical Name:; Molecular weight: 606.71; Formula: C37H38N2O6; Solubility: DMSO (35 mg/ml) Ethanol (20 mg/ml); Physical Properties: Pale-yellow solid; Purity: 95% by HPLC NMR (Conforms)