DATASHEET
Formulation
Off white or yellow solid
Storage:
-20°C
Product Information:
A potent inhibitor of Wnt signaling (IC50=180 nM).1 Inhibits zebrafish tailfin regeneration (0.5 mM).2 Acts via inhibition of tankyrase and attenuates Wnt/b-catenin signaling in cancer stem-like cells.3 Promotes self-renewal and maintains pluripotency of human embryonic stem cells.4 Promotes differentiation of pluripotent stem cells into cardiomyocytes.5
Description:
CAS Number: 1127442-82-3; Chemical Name: 4-(1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl)-N-8-quinolinyl-benzamide; Molecular weight: 409.44; Formula: C25H19N3O2; Solubility: DMSO (10 mg/ml); Physical Properties: Off white or yellow solid; Purity: 98% by TLC/HPLC NMR (Conforms)