bs-83135C
[Life Science]
Cantharidin
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Inhibits protein phosphatase 2A (Ki=0.19 μM) and PP1 (Ki=1.1 μM)1. Displays >500-fold selectivity over PP2B. Suppresses growth and migration of PANC-1 pancreatic cancer cells via phosphorylation and degradation of β-catenin2. Arrests G2/M transition via JNK/Sp1-dependent down-regulation of CDK13. Cell permeable. Warning: Avoid skin contact, may cause skin irritation or blistering.
Description:
CAS Number: 56-25-7<br></br>Chemical Name: Phosphatase PP2A inhibitor<br></br>Molecular Weight: 196.20<br></br>Formula: C10H12O4<br></br>Solubility: DMSO (20 mg/ml) Ethanol (5 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC [5% methanol/methylene chloride; Rf = 0.40] NMR (Conforms)
Size: 100mg,20mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.