bs-83136C

DATASHEET

Formulation Off-White solid

Storage: RT

Product Information:

Ketoconazole is a broad spectrum antifungal agent which acts via inhibition of a cytochrome P450, CYP51A1 which is a lanosterol 14-demethylase.1 Also inhibits CYP3A and CYP1A1.2 Inhibits adrenal steroidogenesis.3 Downregulates cholesterol synthesis in drug-tolerant human lung cancer cell lines.4 Blocks the biosynthesis of leukotrienes (LT) via inhibition of 5-lipoxygenase and dose dependently inhibits LT-mediated bronchoconstriction in guinea pigs.5

Description:

CAS Number: 65277-42-1; Chemical Name: Cytochrome P450 inhibitor; Molecular Weight: 531.43; Formula: C26H28Cl2N4O4; Solubility: DMSO (25 mg/ml); Ethanol (20 mg/ml); Physical Properties: Off-white solid; Purity: >98% by TLC

Size: 100mg, 500mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.