DATASHEET
Formulation
Orange solid
Storage:
RT
Product Information:
Potent and selective protein kinase C inhibitor (IC50 = 10 nM; cAMP-dependent protein kinase IC50 = 2 µM and phosphorylase kinase IC50 = 0.7 µM). Inactive against the tyrosine kinases EGFR, PGDFR and Insulin receptor. Potent inhibitor of GSK-3β in cell lysates (IC50 = 360nM) and GSK-3β immunoprecipitates (IC50 = 170nM) derived from rat epididymal adipocytes.2 Cell permeable.
Description:
CAS Number: 133052-90-1<br></br>Chemical Name: PKC inhibitor<br></br>Molecular Weight: 412.49<br></br>Formula: C25H24N4O2<br></br>Solubility: DMSO (10 mg/ml)<br></br>Physical Properties: Orange solid<br></br>Purity: 98% by TLC NMR conforms