DATASHEET
Formulation
Orange solid
Storage:
-20°C
Product Information:
A potent inhibitor of multiple receptor tyrosine kinases including VEGFR, PDGFRβ and Kit (Ki = 2-17 nM)1. Also inhibits cFMS (IC50=7 nM)2 and FLT33. Potent inhibitor of angiogenesis4. Clinically useful anticancer agent. Cell permeable.
Description:
CAS Number: 341031-54-7; Chemical Name: VEGFR, PDGFR kinase inhibitor; Molecular Weight: 532.57; Formula: C22H27FN4O4 ∙ C4H6O5; Solubility: DMSO (13 mg/ml); Physical Properties: Orange solid; Purity: 98% by TLC, NMR (Conforms)