DATASHEET
Formulation
Orange solid
Storage:
-20°C
Product Information:
A potent inhibitor of multiple receptor tyrosine kinases including VEGFR, PDGFRβ and Kit (Ki = 2-17 nM)1. Also inhibits cFMS (IC50=7 nM)2 and FLT33. Potent inhibitor of angiogenesis4. Clinically useful anticancer agent. Cell permeable.
Description:
CAS Number: 341031-54-7<br></br>Chemical Name: VEGFR, PDGFR kinase inhibitor<br></br>Molecular Weight: 532.57<br></br>Formula: C22H27FN4O4 ∙ C4H6O5<br></br>Solubility: DMSO (13 mg/ml)<br></br>Physical Properties: Orange solid<br></br>Purity: 98% by TLC, NMR (Conforms)