bs-83151C
[Life Science]
Rapamycin
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Clinically useful immunosuppressant. Inhibits the response to interleukin-2 blocking activation of T- and B-cells.1 Rapamycin forms a complex with cytosolic FK-binding protein 12 (FKB12) that binds to mTOR Complex1(mTORC1) inhibiting the mammalian target of rapamycin (mTOR).2 Also binds to mTORC2 leading to decreased glucose tolerance and insensitivity to insulin.3 Induces autophagy.4
Description:
CAS Number: 53123-88-9<br></br>Chemical Name: mTOR inhibitor<br></br>Molecular Weight: 914.17<br></br>Formula: C51H79NO13<br></br>Solubility: DMSO (40 mg/ml) Ethanol (90 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% NMR Conforms
Size: 50mg, 10mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.