DATASHEET
Formulation
yellow solid
Storage:
-20°C
Product Information:
Binds to the N-terminal domain of valosin-containing protein (VCP), an essential protein for autophagosome maturation. Xanthohumol inhibits the function of VCP thereby impairing autophagosome maturation and resulting in accumulation of the microtubule-associated protein 1 light chain 3-II (LC3-II)1. Impairs prostate cancer cell growth and proliferation2. Cell permeable.
Description:
CAS Number: 6754-58-1; Chemical Name: VCP inhibitor / Autophagy inhibitor; Molecular Weight: 354.41; Formula: C21H22O5; Solubility: DMSO (35 mg/ml) Ethanol (35 mg/ml); Physical Properties: Yellow solid; Purity: 98% by TLC, NMR (Conforms)