DATASHEET
Formulation
Yellow solid
Storage:
-20°C
Product Information:
Binds to the N-terminal domain of valosin-containing protein (VCP), an essential protein for autophagosome maturation. Xanthohumol inhibits the function of VCP thereby impairing autophagosome maturation and resulting in accumulation of the microtubule-associated protein 1 light chain 3-II (LC3-II)1. Impairs prostate cancer cell growth and proliferation2. Cell permeable.
Description:
CAS Number: 6754-58-1<br></br>Chemical Name: VCP inhibitor / Autophagy inhibitor<br></br>Molecular Weight: 354.41<br></br>Formula: C21H22O5<br></br>Solubility: DMSO (35 mg/ml) Ethanol (35 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by TLC, NMR (Conforms)