bs-83167C
[Life Science]
ODQ
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800.501.7654 [DOMESTIC]
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Pale-yellow solid
Storage: -20°C
Product Information:
A potent and selective inhibitor of soluble guanylyl cyclase (sGC), IC50 = 20 nM).1 ODQ acts via competition with NO for the heme site of sGC where it binds irreversibly.2 ODQ does not inhibit NO-mediated macrophage toxicity, an activity that is unrelated to cGMP nor does it inhibit particulate GC.1 ODQ is an extremely useful tool to explore the involvement of the NO-cGMP pathway in cellular signaling and physiologic processes.3-5
Description:
CAS Number: 41443-28-1<br></br>Chemical Name: Soluble guanylyl cyclase inhibitor<br></br>Molecular Weight: 187.15<br></br>Formula: C9H5N3O2<br></br>Solubility: DMSO (40 mg/ml)<br></br>Physical Properties: Pale-yellow solid<br></br>Purity: 98% by HPLC NMR (conforms)
Size: 25mg, 5mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.