DATASHEET
Formulation
Orange solid
Storage:
-20°C
Product Information:
Potent and selective inhibitor of the histone acetyl transferase p300/CBP (Ki=400 nM ). Induces apoptosis in prostate cancer cells. Enhances fear extinction memory and synaptic plasticity in mice. Promotes tau deacetylation reducing levels of pathogenic p-tau. Cell permeable.
Description:
CAS Number: 328968-36-1; Chemical Name: HAT inhibitor; Molecular Weight: 445.44; Formula: C24H19N3O6; Solubility: DMSO (10 mg/ml); Physical Properties: Orange solid; Purity: 98% by TLC, NMR conforms