DATASHEET
Formulation
White Solid
Storage:
RT
Product Information:
Hydroxychloroquine sulfate is a lysosomotropic agent which inhibits autophagy and triggers apoptosis in a variety of cell types.1,2 Augments the anticancer activity of DNA-damaging chemotherapy.3 Antiinflammatory activity. Decreases cell surface expression of TNFα receptors in U937 cells.4 Hydroxychloroquine sulfate has been used to treat alopecia successfully5 and is a clinically useful antimalaria agent. Cell permeable and active in vivo.
Description:
CAS Number: 747-36-4; Chemical Name: Autophagy inhibitor; Molecular Weight: 433.96; Formula: C18H26ClN3O · H2SO4; Solubility: water (40mg/ml) DMSO (nil); Physical Properties: White solid; Purity: 98% by TLC, NMR (Conforms)