DATASHEET
Formulation
Off-white solid
Storage:
-20°C
Product Information:
Potent and selective Src family kinase inhibitor. Inhibits Lck(IC50=4 nM); Fyn (IC50=5 nM); Hck (IC50=5 nM). It displays weak inhibition of EGFR (IC50=480 nM) and no inhibition of ZAP-70 (IC50> 100 μM) and JAK2 (IC50> 50 μM)1. It is a useful probe for exploring the involvement of Src family kinases in signal transduction pathways2.
Description:
CAS Number: 172889-27-9<br></br>Chemical Name: Src family kinase inhibitor<br></br>Molecular Weight: 301.78<br></br>Formula: C15H16ClN5<br></br>Solubility: DMSO (25 mg/ml) Ethanol (3 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC, NMR (Conforms)