bs-83208C
[Life Science]
AK-7
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White solid
Storage: RT
Product Information:
A selective Sirt2 inhibitor (IC50=15.5 µM) which does not inhibit Sirt1 or Sirt31. It down regulates cholesterol biosynthesis genes in primary striatal neurons1. Displays neuroprotective effects in Huntington’s disease mouse models including improved motor function, extended survival and reduced brain atrophy all of which were associated with reduced aggregated mutant huntingtin2.
Description:
CAS Number: 420831-40-9<br></br>Chemical Name: SIRT2 inhibitor<br></br>Molecular Weight: 437.36<br></br>Formula: C19H21BrN2O3S<br></br>Solubility: DMSO (50 mg/ml) Ethanol (8 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 25mg, 5mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.