bs-83216C
[Life Science]
AdipoRon
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800.501.7654 [DOMESTIC]
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White solid
Storage: RT
Product Information:
A novel potent and selective adiponectin (AdipoR1 and AdipoR2) receptor agonist, Kd=1.8 and 3.1 μM respectively1. Displayed similar effects to adiponectin in muscle and liver such as activation of PPARα and AMPK signaling pathways. It also reversed insulin resistance and glucose intolerance in mice on a high-fat diet. It ameliorated diabetes in a genetically obese mouse model and prolonged the shortened lifespan of db/db mice on a high-fat diet1. Active in vivo.
Description:
CAS Number: 924416-43-3<br></br>Chemical Name: Adiponection agonist<br></br>Molecular Weight: 428.54<br></br>Formula: C27H28N2O3 <br></br>Solubility: DMSO (40 mg/ml) Ethanol (20 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 50mg, 10mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.